Artichoke (leaf) Extract
● Supports digestive health, influencing lipid metabolism, and regulates glucose and insulin levels (268,269).Organic Turmeric
● May support antioxidant, cardio-protective, anti-inflammatory, anti-microbial, nephro-protective, hepato-protective, immunomodulatory, and anti-rheumatic effects (123).
● May reduce inflammation via decreases of inflammatory markers such as c-reactive protein, interleukin 6, tumor necrosis factor, and decreased cytokine production (123).
● May support joint health via decreases in connective tissue inflammation and improved pain in individuals with osteoarthritis (122).
● May support blood sugar regulation via increased pancreatic beta cell function and improved insulin sensitivity (121).
● May support cardiovascular and liver health via reduced accumulation of advanced glycation end products (AGE), reduced lipid peroxidation, and improved vascular function.
● Curcumin may exhibit antioxidant activity via scavenging of superoxide anion (∙O2−∙) and hydroxyl radicals (∙OH) (scavenging of inflammation molecules) (118,119).
● Curcumin may modulate breast carcinogenesis through its effect on cell cycle and proliferation, apoptosis, senescence, cancer spread and angiogenesis (119).
● May target cancer growth pathways such as the NFkB, PI3K/Akt/mTOR, MAPK and JAK/STAT, (119).
Organic Milk Thistle
● May support liver health, aids as antioxidants, and reduces inflammation (345).
● May support liver health via high amounts of Silymarin which reduces lipid peroxidation and inhibits binding of toxins to the hepatocyte cell membrane receptors (345).
Organic Burdock Root
● May support healthy detoxification, cardiovascular health, skin health, and immune health (356).
● May support immune health through its high levels of antioxidants, polyphenols, and flavonoids, which enhance the adaptive/innate immune response (356).
● May support cardiovascular and skin health by promoting enhanced blood circulation to the skin surface, improving skin quality, and potentially combating skin diseases (356).
● May support antioxidant function through the presence of antioxidant and antidiabetic compounds found in the root, which possess anti-inflammatory effects and potent inhibitory effects that may inhibit malignant growth (356).
Garlic Bulb Extract
● May support cardiovascular health, immune health, joint health, reduced inflammation, gut health, and enhanced antibacterial activity (161).
● May support cardiovascular health via reduced hypertension, reduced total cholesterol, reduced arterial stiffness (hardening of arteries), and markers of atherosclerosis (161).
● May support joint health via reduced NF-κB activation (inflammation) in human fibroblast cells and reduced prevalence of pain in individuals with rheumatoid arthritis (162).
● May support gut health via increased prebiotic properties, increased microbiome population, and increased Lactobacillus and Clostridia species (163).
● May support immune health via a reduction in inflammatory markers (CRP, TNF, IL-6) (164).
Organic Beet Root
● May support cardiovascular, immune health, reduced blood pressure, and optimizes exercise performance (87).
● High in antioxidants such as ascorbic acid, carotenoids, phenolic acids, flavonoids, polyphenols, and anti-inflammatory compounds (betalains) (87).
● Betalains have been shown to inhibit inflammatory pathways (Nuclear Factor-Kappa B “NF-κB”) that manifest in a plethora of chronic diseases (87).
● Increases nitric oxide production optimizing healthy blood pressure and enhanced cardiovascular output during exercise (87).
● Beetroot may support anti-carcinogenic activity by possibly inhibiting cancer cell growth mechanisms (cell proliferation, angiogenesis, and tumorigenesis) (87).
Organic Fennel Seed
● May support joint health via decreased prevalence of intense arthritic symptoms (390).
